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Eslami, Roostam, Hosseini, Mehdi. (1404). Integrated Analytical Characterization of Mineral Nanoparticles Isolated from Baktar Hot Spring Water and Their Antibacterial Performance. فصلنامه علمی زیست فناوری گیاهان زراعی, 12(2), 120-133. doi: 10.30473/ijac.2026.78061.1346
Roostam Jamali Eslami; Mehdi Hosseini. "Integrated Analytical Characterization of Mineral Nanoparticles Isolated from Baktar Hot Spring Water and Their Antibacterial Performance". فصلنامه علمی زیست فناوری گیاهان زراعی, 12, 2, 1404, 120-133. doi: 10.30473/ijac.2026.78061.1346
Eslami, Roostam, Hosseini, Mehdi. (1404). 'Integrated Analytical Characterization of Mineral Nanoparticles Isolated from Baktar Hot Spring Water and Their Antibacterial Performance', فصلنامه علمی زیست فناوری گیاهان زراعی, 12(2), pp. 120-133. doi: 10.30473/ijac.2026.78061.1346
Eslami, Roostam, Hosseini, Mehdi. Integrated Analytical Characterization of Mineral Nanoparticles Isolated from Baktar Hot Spring Water and Their Antibacterial Performance. فصلنامه علمی زیست فناوری گیاهان زراعی, 1404; 12(2): 120-133. doi: 10.30473/ijac.2026.78061.1346

Integrated Analytical Characterization of Mineral Nanoparticles Isolated from Baktar Hot Spring Water and Their Antibacterial Performance

Iranian Journal of Analytical Chemistry
دوره 12، شماره 2 - شماره پیاپی 24، آذر 2025، صفحه 120-133    اصل مقاله (914.49 K)
نوع مقاله: Full research article
شناسه دیجیتال (DOI): 10.30473/ijac.2026.78061.1346
نویسندگان
Roostam Jamali Eslami1؛ Mehdi Hosseini* 2
1Kharazmi Exceptional Talents School, Sonqor Koliaei Education District, Songor, Kermanshah, Iran
2Department of Chemistry, Faculty of Basic Sciences, Ayatollah Boroujerdi University
چکیده
Hot springs are natural geothermal systems enriched with dissolved minerals and nano/micro-sized particles that may contribute to their traditional therapeutic properties. In the present study, mineral nanoparticles (MNPs) were isolated for the first time from the Baktar hot spring located in western Iran, and their physicochemical characteristics as well as antibacterial activity were investigated. Structural analyses using FTIR, XRD, XRF, ICP-MS, and TGA revealed that the particles mainly consist of silicate- and metal oxide-based minerals containing high levels of SiO2 (54.07%), Al2O3 (15.2%), CaO (7.19%), and Fe2O3 (5.45%). ICP-MS analysis also demonstrated the presence of several trace and heavy metals, including Sr (685.9 ppm), V (139 ppm), Cr (105 ppm), Zn (85 ppm), and Cu (63 ppm). XRD analysis estimated an average crystallite size of approximately 49.7 nm. The antibacterial activities of heated and unheated MNPs were evaluated against Staphylococcus aureus ATCC 43300 and Pseudomonas aeruginosa using disk diffusion and minimum inhibitory concentration (MIC) assays. The inhibition zone diameter for unheated MNPs reached 19.0 ± 0.50 mm against P. aeruginosa, whereas lower activity was observed against S. aureus (9.32 ± 0.15 mm). Both heated and unheated particles exhibited an identical minimum inhibitory concentration (MIC) of 150 μg/mL. The results suggest that naturally occurring mineral nanoparticles isolated from the Baktar hot spring possess promising antibacterial properties, supporting the potential role of geothermal mineral systems in balneotherapy and biomedical applications. This study represents the first comprehensive analytical investigation of naturally occurring mineral nanoparticles isolated from the Baktar hot spring and provides new insights into the relationship between their elemental composition, physicochemical characteristics, and antibacterial properties.
کلیدواژه‌ها
Natural mineral nanoparticles؛ trace element determination؛ hot spring water؛ physicochemical characterization؛ antibacterial activity
عنوان مقاله [English]
بررسی تجزیه‌ایی یکپارچه نانوذرات معدنی موجود در آب چشمه آب گرم بکتر با تأکید بر عملکرد ضدباکتریایی
نویسندگان [English]
رستم جمالی اسلامی1؛ مهدی حسینی2
1دبیرستان خوارزمی شهرستان سنقر کلیایی
2گروه شیمی، دانشکده علوم پایه، استادیار شیمی تجزیه-دانشگاه آیت ا...بروجردی
چکیده [English]
چشمه‌های آب گرم، سامانه‌های زمین‌گرمایی طبیعی هستند که با مواد معدنی محلول و ذرات در مقیاس نانو و میکرو غنی شده‌اند و این ویژگی می‌تواند در خواص درمانی سنتی آن‌ها نقش داشته باشد. در این مطالعه، برای نخستین‌بار نانوذرات معدنی (MNPs) از آب چشمه آب گرم بکتر واقع در غرب ایران جدا شده و ویژگی‌های فیزیکوشیمیایی آن‌ها همراه با فعالیت ضدباکتریایی مورد بررسی قرار گرفت. تحلیل‌های ساختاری به‌وسیله طیف‌سنج مادون قرمز تبدیل فوریه (FTIR)، پراش پرتو ایکس (XRD)، فلورسانس پرتو ایکس (XRF)، طیف‌سنجی جرمی پلاسمای جفت‌شده القایی (ICP-MS) و آنالیز گرما‌سنجی (TGA) نشان داد که این ذرات عمدتاً از فازهای سیلیکاتی و اکسیدهای فلزی تشکیل شده‌اند و دارای مقادیر بالایی از SiO2 (07/54%)، Al2O3 (20/15%)، CaO (19/7%)، A Fe2O3 (45/5%) هستند. همچنین نتایج ICP-MS وجود مقادیر قابل توجهی از عناصر کم‌مقدار و فلزات سنگین از جمله استرانسیوم (ppm 9/685)، وانادیوم (ppm 139)، کروم ((ppm 105)، روی (ppm 85) و مس (ppm 63) را تایید کرد. انالیز پراش اشعه ایکس نشان داد که میانگین اندازه ذرات بلوری در حدود 7/49 نانومتر می باشد. فعالیت ضدباکتریایی نانوذرات خام (غیرحرارت‌دیده) و حرارت‌دیده در برابر باکتری‌های Staphylococcus aureus ATCC 43300 و Pseudomonas aeruginosa با استفاده از آزمون نفوذ دیسک و تعیین حداقل غلظت مهارکننده (MIC) ارزیابی شد. قطر ناحیه عدم رشد برای نانوذرات غیرحرارت‌دیده در برابر باکتری P. aeruginosa به 0.5±19 میلی‌متر رسید، در حالی‌که این مقدار برای S. aureus کمتر و برابر 0.15±9.32 میلی‌متر بود. همچنین هر دو نوع نانوذره حرارت‌دیده و غیرحرارت‌دیده، حداقل غلظت مهارکننده 150 میکروگرم بر میلی‌لیتر را نشان دادند. نتایج به‌دست‌آمده نشان داد که نانوذرات معدنی طبیعی موجود در چشمه آب گرم بکتر دارای فعالیت ضدباکتریایی قابل توجهی هستند و می‌توانند نقش بالقوه‌ای در توجیه اثرات درمانی سامانه‌های زمین‌گرمایی و کاربردهای زیست‌پزشکی داشته باشند.
کلیدواژه‌ها [English]
نانوذرات معدنی طبیعی, تعیین مقدار ناچیز عناصر, آب گرم چشمه, آنالیز نانومواد, مهار باکتریایی
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آمار
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