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بررسی اثرات القایی گازوئیل بر پارامترهای کبدی، موش‌های سفید نژاد Albino NMRI | ||
| فصلنامه علمی زیست شناسی جانوری تجربی | ||
| مقاله 9، دوره 4، شماره 3، بهمن 1394، صفحه 79-90 اصل مقاله (865.92 K) | ||
| نوع مقاله: مقاله پژوهشی | ||
| نویسندگان | ||
| زهره فضل الهی1؛ نسیم نعیمی2؛ کبری زارع*3 | ||
| 1دانشگاه رازی کرمانشاه | ||
| 2دانشگاه سیستان و بلوچستان زاهدان | ||
| 3دانشگاه علوم و تحقیقات تهران | ||
| چکیده | ||
| چکیده گازوئیل یکی از محصولات نفتی با کاربردهای فراوان، ترکیبی آروماتیک و مهمترین آلاینده محیط زیست است. با توجه به اثرات مخرب آن بر موجودات زنده و انسان، هدف از این تحقیق، بررسی اثرات خوراکی گازوئیل بر پارامترهای بافت کبد، موش سفید، نژاد Albino NMRI بود. 40 سر، موش در 4 گروه، موش های نر و ماده بالغ هر کدام در دو گروه شاهد و تیمار با میانگین وزنی 28 گرم تقسیم بندی و مورد مطالعه قرار گرفتند. به موش های تیمار در مدت 14 روز، هر روز، یک نوبت cc2/. محلول گازوئیل خالص با عیار mg/kg6/6 وزن موش خورانده شد.پس از بیهوشی و مطالعات ماکروسکوپی و میکروسکوپی از طریق لامهای تهیه شده برخی پارامترهای بافت کبد، با استفاده از نرمافزار موتیک اندازه گیری و مورد تجزیه تحلیلهای آماری با نرمافزار SPSS19 قرار گرفت. بررسی‌ها، در گروه های تیمار نر و ماده نسبت به گروه شاهد، بیانگر افزایش میانگین قطر سیاهرگ مرکز لوبولی، سینوزوئیدها، نسبت سطح هسته به سطح سلول، تعداد سلول های دو هستهای به تک هستهای و کاهش قطر سیاهرگ بین لوبولی بود که این تغییرات در سطح (05/0P | ||
| کلیدواژه‌ها | ||
| گازوئیل؛ پارامترهای کبدی؛ موش سفید نژاد Albino NMRI | ||
| عنوان مقاله [English] | ||
| Investigation of the gasoil inductive effects on liver parameters of white albino NMRI Mice | ||
| نویسندگان [English] | ||
| Zohreh Fazlollahi1؛ Nasim Naeimi2؛ Kobra Zare3 | ||
| چکیده [English] | ||
| Abstract Since Gasoil due to the aromatics of the most important environmental pollutants and is one of the oil with many applications. According to its damaging effects on living organisms and human beings, the purpose of this study was to investigate the effects of Gasoil on the parameters of liver, white rat race was Albino NMRI. The 40 mice in 4 groups, adult male mice were divided into control and treatment of adult female rats were divided into control and treatment, with an average weight of 28 grams divided and studied. In mice treated for 14 days and every day, once 0.2cc Pure fuel-grade solution 6.6 mg/kg mice were fed weight .After anesthesia and studies macroscopic and microscopic slides prepared from liver tissue parameters, using software and the death a measure of statistical analysis software was SPSS19. Studies in male and female treatment groups compared to the control group in the parameters of liver tissue, represents the mean diameter of lobular central vein, sinusoid, the core of the cell to the cell surface and the number of single-core and dual-core to reduce the diameter of the vein between lobular that these changes in level (P | ||
| کلیدواژه‌ها [English] | ||
| Gasoil, Liver Parameters, White Albino NMRI Mice | ||
| مراجع | ||
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