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کاربرد نانوذرات Fe2O3 به عنوان کاتالیزور جدید در سنتز سه‌جزئی و تک ظرف مشتق‌های 2- آمینو-H4-پیران-3- کربونیتریل در حلال آب | ||
| دوفصلنامه شیمی آلی | ||
| دوره 1، شماره 1، اردیبهشت 1401، صفحه 149-162 اصل مقاله (921.91 K) | ||
| نوع مقاله: مقاله پژوهشی | ||
| نویسندگان | ||
| کلثوم ملایی نژاد1؛ سید حسین بنی طبا* 2 | ||
| 1دانشجوی کارشناسی ارشد رشته شیمی آلی دانشگاه پیام نور. ایران. | ||
| 2استادیار شیمی آلی دانشگاه پیام نور. ایران. | ||
| چکیده | ||
| با توجه به اصول شیمی سبز، نانوذرات مغناطیسی فضای جدیدی را برای معرفی سیستم‌های کاتالیزوری مؤثر، از جهت عملکرد بهتر و جداسازی کاتالیزور در روش‌های گوناگون سنتز مواد آلی، ایجاد کرده‌اند. همچنین، استفاده از حلّال‌های سبز و دوستدار محیط‌زیست، به همراه نانواکسیدهای فلزی، در تهیه ترکیب‌های ناجور حلقه از اهمیت ویژه‌ای برخوردار است. در این کار پژوهشی تراکم سه‌جزئی میان کوجیک اسید، مالونونیتریل و آلدهیدهای آروماتیک، در حضور کاتالیزور نانوذرات Fe2O3 در حلّال آب، به‌منظور تهیه مشتق‌های 2-آمینو-H4 پیران-3-کربونیتریل، به‌عنوان یک روش کاملاً جدید ارائه شده است. استفاده از نانوذرات اکسید آهن (III) اثر کاتالیزوری بسیار بالایی را نسبت به دیگر نانواکسیدهای فلزی مثل TiO2، MgO، ZrO2، SiO2 نشان داده است. استفاده از حلّال آب به‌عنوان یک حلّال دوستدار محیط‌زیست، دارای زمان کوتاه واکنش و بازده بالا از مزایای این کار پژوهشی است. ساختار محصولات را توسط IR و 1H-NMR بررسی کرده‌ایم. | ||
| کلیدواژه‌ها | ||
| نانوذرات اکسید آهن (III)؛ 2-آمینو-H4-پیران-3-کربونیتریل؛ واکنش سه‌جزئی؛ شرایط تک ظرف؛ شیمی سبز؛ محیط آبی | ||
| عنوان مقاله [English] | ||
| The Application of Fe2O3 Nanoparticles as New Catalyst in Three Component and One-Pot Synthesis of 2-Amino-4H-Pyrane-3-Carbonitrile in Water | ||
| نویسندگان [English] | ||
| Kolsoom Molayinezhad1؛ Seyed Hossein Banitaba2 | ||
| 1M.A Student of organic chemistry, Payam Noor University, Iran. | ||
| 2Departement of chemistry, Payam Noor University, Tehran, Iran. | ||
| چکیده [English] | ||
| According to the green chemistry’s approaches, magnetite nanoparticles (MNPs) open up new fields to introduce an efficient system for better catalyst activity and facilitating catalyst recovery in different procedures. Therefore, in this paper, a mild and simple reaction to synthesize substituted pyranopyranes via multi-component reaction catalyzed by Fe2O3 nanoparticles as new method is reported. Using Fe2O3 nanoparticles show better catalytic activity towards other nanometal oxides such as TiO2, MgO, ZrO2, and SiO2. Also the use of water as green and environmental friendly solvent, high yields and short routine are the advantages of this work. Furthermore, the structural of the new product was deducted by IR, 1HNMR spectroscopy. | ||
| کلیدواژه‌ها [English] | ||
| Fe2O3 Nanoparticles, 2-Amino-Dihydropyrano [3, 2-b] pyran-3-Carbonitriles, Three-Component Reaction, One-Pot Conditions, Green Chemistry, Aqueous Media | ||
| مراجع | ||
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