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A novel and efficient synthesis of bisindolyl methanes with using silica-supported 3-(triethoxysilyl) propane-1-ammonium chloride as reusable catalyst under solvent free conditions | ||
| Iranian chemical communication | ||
| مقاله 31، دوره 4، Issue 4, pp. 359-490, Serial No. 13، دی 2016، صفحه 433-448 اصل مقاله (943.47 K) | ||
| نوع مقاله: Original Research Article | ||
| نویسندگان | ||
| Mohammad Reza Poor Heravi* 1؛ Aazam Monfared Monfared2؛ Masoumeh Ahmadi2 | ||
| 1Department of Chemistry, Payame Noor University, Abhar, Iran | ||
| 2Department of Chemistry, Payame Noor University, P.O. Box 19395-3697, Tehran, Iran | ||
| چکیده | ||
| A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different conditions and optimized. The use of just 0.02 g of (silica gel-ammonium salt) is sufficient. The reaction was carried out at 110 °C under thermal condition. This method, including some advantages such as mild reaction condition, easy work-up, and recoverable and reusable catalyst. A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different conditions and optimized. The use of just 0.02 g of (silica gel-ammonium salt) is sufficient. The reaction was carried out at 110 °C under thermal condition. This method, including some advantages such as mild reaction condition, easy work-up, and recoverable and reusable catalyst.. | ||
| کلیدواژهها | ||
| Bis(indolyl)methanes؛ multicomponent reactions؛ silica-supported 3-(triethoxysilyl) propane-1-ammonium chloride؛ solvent-free conditions | ||
| مراجع | ||
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