پیوندهای مفید
اخبار و اعلانات
آمار
| تعداد نشریات | 48 |
| تعداد شمارهها | 1,242 |
| تعداد مقالات | 10,688 |
| تعداد مشاهده مقاله | 21,874,016 |
| تعداد دریافت فایل اصل مقاله | 14,703,055 |
A green synthesis of functionalized thiazol-2(3H)-imine via a three-component tandem reaction in ionic liquid media | ||
| Iranian chemical communication | ||
| مقاله 4، دوره 5، Issue 3, pp. 237-363, Serial No. 16، مهر 2017، صفحه 262-267 اصل مقاله (648.53 K) | ||
| نوع مقاله: Original Research Article | ||
| نویسندگان | ||
| Ashraf Sadat Shahvelayati* ؛ Leila Hajiaghababaei؛ Akram Panahi Sarmad | ||
| Department of Chemistry, Yadegar-e-Imam Khomeini (RAH) Shahre-rey Branch, Islamic Azad University, Tehran, Iran | ||
| چکیده | ||
| In this research, an efficient synthesis toward 2-(2-((4-Methoxybenzoyl)imino)-4-(4-methoxyphenyl)thiazol-3(2H)-yl)-2-phenylacetic acid via a three-component tandem reaction using aroylisothiocyanate, phenyl glycine, and 4-methoxyphenacyl bromide in an ionic liquid (IL) has been described. 1-Methyl-3-pentylimidazolium bromide (IL) has been employed as a recyclable green solvent. The work-up procedure was fairly simple and the product did not require further purification. The influence of various reaction parameters such as solvent, temperature, and time was examined and among the various solvents such as ethanol, acetonitrile, n-hexane, water, and ionic liquid for synthesis of the final product, the best result was obtained in 1-methyl-3-pentylimidazolium bromide at 50oC for 1 hours. | ||
| کلیدواژهها | ||
| Thiazol-2(3H)-imine؛ α-bromoketone؛ ionic liquid؛ phenyl glycine؛ tandem reacrion, aroylisothiocyanate | ||
| مراجع | ||
|
[1] Z. Hossaini, F. Rostami Charatib, R. Hajinasiria, Iran. J. Org. Chem., 2010, 2, 515-518.
[2] V. Deepti, M. Aruna Kumari, N. Harikrishna, G. Ramesh, C. Venkata Rao, Der. Pharma Chem.,2013, 5, 181-184.
[3] A. Andreani, M. Rambaldi, G. Mascellani, R. Bossa, I. Galatulas, Eur. J. Med. Chem.,1986, 21, 451-453.
[4] H. Tripathi, S.N. Mahapatra, J. Ind. Chem. Soc., 1975, 52, 766-767.
[5] A.Z. Amrita, G.P. Senthilkumar, Der. Pharma Chem., 2011, 3, 523-537.
[6] A. Geronikaki, G. Theophilidis, Eur. J. Med. Chem., 1992, 27, 709-716.
[7] K.F.M. Kamal, O.O.M. Farahat, A.Z.A. Ahmed, M.G. Marei, Molecules., 2011, 16, 5496-5506.
[8] T. Giridhar, R.B. Reddy, B. Prasanna, G.V.P. Chandra Mouli, Ind. J. Chem., 2001, 40B, 1279-1281.
[9] H. Beyzaei, R. Aryan, H. Moghadas, J. Serb. Chem. Soc., 2015, 80, 453-458.
[10] V.K. Guptaa, A.K. Singha, L.K. Kumawat, Electrochim. Acta., 2013, 95, 132-138.
[11] I.A. Pechenkina, K.N. Mikhelsonz, Russ. J. Electrochem., 2015, 5, 93–102.
[12] L. Hajiaghababaei, A.S. Shahvelayati, S.A.Aghili, Anal. Bioanal.Electrochem., 2015, 7, 91-104. [13] S.E. Bramley, V. Dupplin, D.G.C. Goberdhan, G.D. Meakins, J. Chem. Soc. Perkin. Trans., 1987, 1, 639-643.
[14] P. Wasserscheid, T. Welton (Eds.), Ionic liquids in synthesis, Wiley, Weinheim, 2003.
[15] I. Yavari, R. Hajinasiri, S.Z. Sayyed-Alangi, N. Irvani, J. Iran. Chem. Soc., 2009, 6, 705-710.
[16] R. Hajipour, F. Rafiee, J. Iran. Chem. Soc., 2009, 6, 647-652.
[17] I. Yavari, A.S. Shahvelayati, A. Malekafzali, J. Sulfur Chem., 2010, 3, 499–508.
[18] I. Yavari, M. Ghazvini, A.S. Shahvelayati, M.M. Ghanbari, Phosphorus Sulfur Silicon Relat. Elem., 2011, 186, 134–139.
[19] I. Yavari, A.S. Shahvelayati, Phosphorus Sulfur Silicon Relat. Elem., 2010, 185, 1726–1731.
[20] Y.S. Vygodskii, E.I. Lozinskaya, A.S. Shaplov, Macromol. Rapid. Commun., 2002, 23, 676–679. | ||
|
آمار تعداد مشاهده مقاله: 1,855 تعداد دریافت فایل اصل مقاله: 1,742 |
||