پیوندهای مفید
اخبار و اعلانات
آمار
| تعداد نشریات | 37 |
| تعداد شماره‌ها | 1,001 |
| تعداد مقالات | 8,542 |
| تعداد مشاهده مقاله | 15,321,114 |
| تعداد دریافت فایل اصل مقاله | 10,720,809 |
LaCl3.7H20: An efficient catalyst for one-pot multi-component synthesis of 1,4-polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction | ||
| Iranian chemical communication | ||
| مقاله 8، دوره 5، Issue 3, pp. 237-363, Serial No. 16، مهر 2017، صفحه 293-300 اصل مقاله (583.98 K) | ||
| نوع مقاله: Original Research Article | ||
| نویسندگان | ||
| Abhijeet Somwanshi1؛ Yashwant Bhaskar Pandit2؛ Akash Gholap3؛ Rushikesh Ghogare4؛ Shivaji Pandit* 5 | ||
| 1Research Centre and Post Graduate Department of Chemistry, PadmashriVikhePatil College of Arts, Science and Commerce Pravaranagar At./Po. Lonikd. Tal.Rahata. Dist. Ahmednagar. 413713. (MS). India. (Affiliated to SavitribaiPhule Pune University, Pune) | ||
| 2Applied Chemistry Division, DIAT-DRDO, Girinagar, Pune. 411025.(MS) India. | ||
| 3Research Centre and Post Graduate Department of Chemistry, PadmashriVikhe Patil College of Arts, Science and Commerce Pravaranagar At./Po. Lonikd. Tal.Rahata. Dist. Ahmednagar. 413713. (MS). India. (Affiliated to Savitribai Phule Pune University, Pune) | ||
| 4Research Centre and Post Graduate Department of Chemistry, Padmashri Vikhe Patil College of Arts, Science and Commerce Pravaranagar At./Po. Lonikd. Tal.Rahata. Dist. Ahmednagar. 413713. (MS). India. (Affiliated to Savitribai Phule Pune University, Pune) | ||
| 5Post Graduate and Research Centre, Department of Chemistry, Padmashri Vikhe Patil College of Arts, Science and Commerce Pravaranagar, (Loni kd) Tal. Rahata. Dist. Ahmednagar 413713 (MS) India. | ||
| چکیده | ||
| An efficient one pot multi component synthesis of 1, 4-Polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction using lanthanum chloride heptahydrate (LaCl3.7H2O) from an aromatic aldehyde, ethyl acetoacetate, dimedone and ammonium acetate as a nitrogen precursor in ethanol at room temperature is described. In the present work we report lanthanum chloride heptahydrate remarkably non-toxic in nature and ease of handling we explored the utility of lanthanum chloride as a catalyst for the synthesis of 1, 4-polyhydroquinoline derivatives. We newly report p-N, N-dimethylamino-cinnamaldehyde and m-chlorobenzaldehyde for the synthesis of 1, 4-Polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction and was characterized by IR and 1HNMR spectroscopic methods. | ||
| کلیدواژه‌ها | ||
| Hantzsch reaction؛ lanthanum chloride heptahydrate؛ Polyhydroquinoline derivatives؛ Aromatic aldehydes | ||
| مراجع | ||
|
[1] (a) F. Bertozzi, M. Gustafsson and R. Olsson, Org. Lett., 2002, 4, 3147-3150. (b) B.M. Trost, Angew Chem. Int. Ed. Engl., 1995, 34, 259-281. (c) A. Domling and I. Ugi, Angew. Chem. Int. Ed., 2000, 39, 3168-3210.
[2] M. Nikpassand, M. Mamaghani and K. Tabataba, Molecules, 2009, 14, 1468-1474.
[3] (a) R. Simsek, U.B. Ismailoglu, C. Safak and I. Sahin-Erdemli, Farmaco, 2000, 55, 665-668. (b) Y.L. Chen, K.C. Fang, J.Y. Sheu, S.L. Hsu and C.C. Tzeng, J. Med. Chem., 2001, 44, 2374-2377. (c) G. Roma, M.D. Braccio, G. Grossi and M. Chai, Eur. J. Med. Chem., 2000, 35, 1021-1035. (d) M.P. Maguire, K.R. Sheets, K. Mcvety, A.P. Spada and A. Ziberstein, J. Med. Chem., 1994, 37, 2129-2137.
[4] S. Ko, M.N.V. Sastry, C. Lin and C. Yao, Tett. Lett., 2005, 46, 5771-5774.
[5] G. Sabitha; G.S.K.K. Reddy, S. Ch. Reddy and J.S. Yadav, Tett. Lett., 2003, 44, 4129-4131.
[6] R. Sridhar and P.T. Perumal, Tetrahedron, 2005, 61, 2465-2470.
[7] B. Das, B. Ravikanth, R. Ramu, B.V. Rao, Chem. Pharm. Bull., 2006, 54, 1044-1045.
[8] S. Ko and C.F. Yao, Tetrahedron, 2006, 62, 7293-7299.
[9] S.R. Cherkupally and R. Mekalan, Chem. Pharm. Bull., 2008, 56, 1002-1004.
[10] M.M. Heravi, K. Bakhtriri, N.M. Javadi, F.F. Bamoharram, M. Saeedi and H.A. Oskoo, J. Mol. Catal. A Chem., 2007, 264, 50-52.
[11] N.N. Karade, H.V. Budhewar, V.S. Shinde and W.N. Jadhav, Lett. Org. Chem., 2007, 4, 16-19.
[12] C.S. Reddy and M. Raghu, Indian J. Chem., 2008, 47B, 1578-1582.
[13] L.M. Wang, J. Sheng, L. Zhang, J.W. Han, Z. Fan, H. Tian and C.T. Qian, Tetrahedron, 2005, 61, 1539-1543.
[14] A. Khazaei, A.R. Moosavi-Zare, H. Afsar – Hezarkhani and V. Khakyzadeh, RSC Adv., 2014, 4, 32142-32147.
[15] G. Song, B. Wang, X. Wu, Y. Kang and L. Yang L, Synth.Commun., 2005, 35, 2875-2880.
[16] J.S. Yoo, T.J. Lauglin, J.J. Krob and R.S. Mohan, Tett. Lett., 2015, 56, 4060-4062.
[17] S.B. Sapkal, K.F. Shelke, B.B. Shingate and M.S. Shingare MS, Tett. Lett., 2009, 50, 1754-1756.
[18] L. Ohberg and J. Westman, Synlett, 2001, 1296-1298.
[19] P. Arumugam and P.T. Perumal, Indian J. Chem. Sec. B, 2008, 47B, 1084-1090.
[20] S. Kumar, P. Sharma, K.K. Kapoor and M.S. Hundal, Tetrahedron, 2008, 64, 536-542.
[21] S.R. Kumar, Y. Venkateswaralu and P. Leelavathi, Organic Synthesis and Medicinal Chemistry, 2012, 1, 11-14.
[22] A.V. Narsaiah, Lett. Org. Chem., 2007, 4(7), 462-464.
[23] J.L. Luche and A.L. Gemal, Chem. Commun., 1978, 976-977.
[24] A.V. Narsaiah and K. Nagaiah, Indian J. Chem., Sec. B, 2003, 42B, 2045-2047.
[25] A.V. Narsaiah, J. Orgnomet. Chem., 2007, 692. 3614-3618.
[26] J. Lu, Y. Bai, Z. Wang, B. Yang and H. Ma, Tett. Lett., 2000, 41, 9075-9078.
[27] S.S. Pandit, B.D. Vikhe and G.D. Shelke, J. Chem. Sci., 2007, 119, 295-297. | ||
|
آمار تعداد مشاهده مقاله: 1,648 تعداد دریافت فایل اصل مقاله: 1,155 |
||