اخبار و اعلانات

 آمار

تعداد نشریات48
تعداد شماره‌ها1,235
تعداد مقالات10,619
تعداد مشاهده مقاله21,515,901
تعداد دریافت فایل اصل مقاله14,479,930
Soleimany, Mehdi, Lari, Jalil, Vahedi, Hooshang. (1392). Synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidin-3(4H)-amine. فصلنامه علمی زیست فناوری گیاهان زراعی, 2(Issue 1, pp. 1-81, Serial No. 2), 18-26.
Mehdi Soleimany; Jalil Lari; Hooshang Vahedi. "Synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidin-3(4H)-amine". فصلنامه علمی زیست فناوری گیاهان زراعی, 2, Issue 1, pp. 1-81, Serial No. 2, 1392, 18-26.
Soleimany, Mehdi, Lari, Jalil, Vahedi, Hooshang. (1392). 'Synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidin-3(4H)-amine', فصلنامه علمی زیست فناوری گیاهان زراعی, 2(Issue 1, pp. 1-81, Serial No. 2), pp. 18-26.
Soleimany, Mehdi, Lari, Jalil, Vahedi, Hooshang. Synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidin-3(4H)-amine. فصلنامه علمی زیست فناوری گیاهان زراعی, 1392; 2(Issue 1, pp. 1-81, Serial No. 2): 18-26.

Synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidin-3(4H)-amine

Iranian chemical communication
مقاله 2، دوره 2، Issue 1, pp. 1-81, Serial No. 2، فروردین 2014، صفحه 18-26    اصل مقاله (267.09 K)
نوع مقاله: Original Research Article
نویسندگان
Mehdi Soleimany* 1؛ Jalil Lari2؛ Hooshang Vahedi3
1Nothing
2Associate Professor
3Assistant Professor
چکیده
The synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzo thieno[2,3-d]pyrimidin-3(4H)-amine 3 has been developed in 3 steps through the reaction of heteroaromatic o-aminonitrile 1 with triethyl orthoformate afforded the corresponding imido ester 2 followed by cyclization with hydrazine hydrate to furnish iminothienopyrimidineamine 3 and finally the imination of 3 at room temperature with aromatic aldehydes was generated the corresponding imines (5a-5h). The new products were obtained in high yield with an easy work-up in simple reaction along with the purification of products by non-chromatographic method. This general synthetic procedure can be extended to the preparation of wide variety of imines using o-aminonitrile bifunctional derivatives which synthesized by Gewald reaction.
کلیدواژه‌ها
N-(Arylmethylene)-4-imino-5؛ 6؛ 7؛ 8-tetrahydro-1-benzothieno[2؛ 3-d]pyrimidin-3(4H)-amines
اصل مقاله

Click on Google Scholar  for all information of this Article in google Scholar

مراجع
[1]   F.Ahmeda,M.H.Hanna,M.F.Eman,E.AbdEl-Galil,World.J. Chem., 2009, 4, 58-65.

[2]   N.Lakshmi,V.Haritha,V.Sreeram,D.Ra-jalakshmi,Rasayan. J. Chem., 2009, 2, 71-74.

[3]   M.D.Salahuddin,K.Sunil,S.M.Shantakumar,E-Journal of Chemistry, 2009, 6, 801-808.

[4]   L.P.Melissa,C.G.Wayne,E.J.Tara,A.N.Ja-son,Bioorg. Med. Chem.Lett., 2003, 13, 107-110.

[5]    V. Alagarsamy, S.Vijayakumar,S.V. Raja, Biomed. Pharma., 2007,61, 285-291.

[6]   A.V. Bol´but, M.V. Vovk, Abstracts of Interna- tional  Confeerence on  the Chemistry of  Nitrogen Containing Heterocycles, CNH-2003, Kharkiv (Ukraine), 2003, p. 68.

[7]   C.J. Shishoo, V.S. Shirsath, I.S. Rathod, V.D. Yande, Eur. J. Med. Chem., 2000, 35, 351-358.

[8]   S.Sasaki,N.Cho, Y.Nara,M.Harada,S.Endo, N.Suzuki, Sh.Furuya,M. Fujino, J. Med. Chem., 2003, 46, 113-124.

[9]   B.V. Ashalatha, B. Narayana, R.K. Vijaya, K.N. Suchetha, Eur. J. Med. Chem., 2007, 42, 719-728.

[10]           V.Alagarsamy,D.Shankar,V.R.Solomon, Arkivoc, 2006, 11, 149-159.

[11]                       I.O.Donkor, H. Li,  S.F. Queener,Eur. J. Med. Chem., 2003, 38, 605-611.

[12]           C.J.Shishoo,M.B.Devani,U.S.Pathak,S. Ananthan, V.S.Bhadti,G.V. Ullas,K.S.Jain,I.S. Rathod,D.S.Talati,N.H. Doshi,J. Heterocycl. Chem., 1984, 21, 375-380.

[13]           Z.Csuros, R.Soos,J. Palinkas,I.Bitter,Acta. Chim., 1971, 68, 397-402.

[14]           F.Sauter,Monatsh.Chem.,1970,101,535-543.

[15]           H. Link,Helv. Chim. Acta., 1990, 73, 797-803.

[16]           A. Davoodnia, M.Bakavoli,M.Soleimany,N. Tavakoli-Hoseini,Monatsh.Chem.,2009,140,355-358.

[17]           K.Gewald,E.Schinke,H.Boettcher,Chem. Ber., 1966, 99, 94-100.

آمار
تعداد مشاهده مقاله: 3,017
تعداد دریافت فایل اصل مقاله: 2,748


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب