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Oftadeh, Mohsen, Saghaie, Lotfollah, Pirialam, Shahla. (1393). Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds. فصلنامه علمی زیست فناوری گیاهان زراعی, 2(Issue 2, pp. 82-163, Serial No. 3), 82-92.
Mohsen Oftadeh; Lotfollah Saghaie; Shahla Pirialam. "Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds". فصلنامه علمی زیست فناوری گیاهان زراعی, 2, Issue 2, pp. 82-163, Serial No. 3, 1393, 82-92.
Oftadeh, Mohsen, Saghaie, Lotfollah, Pirialam, Shahla. (1393). 'Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds', فصلنامه علمی زیست فناوری گیاهان زراعی, 2(Issue 2, pp. 82-163, Serial No. 3), pp. 82-92.
Oftadeh, Mohsen, Saghaie, Lotfollah, Pirialam, Shahla. Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds. فصلنامه علمی زیست فناوری گیاهان زراعی, 1393; 2(Issue 2, pp. 82-163, Serial No. 3): 82-92.

Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds

Iranian chemical communication
مقاله 1، دوره 2، Issue 2, pp. 82-163, Serial No. 3، تیر 2014، صفحه 82-92    اصل مقاله (429.4 K)
نوع مقاله: Original Research Article
نویسندگان
Mohsen Oftadeh* 1؛ Lotfollah Saghaie2؛ Shahla Pirialam1
1Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
2Department of Medicinal Chemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar Jerib, 81746-73461 Isfahan, I. R. of Iran.
چکیده
Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically invest
کلیدواژه‌ها
Hydroxypridinone؛ partition coefficient؛ chelating agent؛ density functional theory
مراجع
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