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Pharmacological properties of some 3-substituted indole derivatives, a concise overview | ||
| Iranian chemical communication | ||
| مقاله 7، دوره 2، Issue 4, pp. 236-325, Serial No. 5، دی 2014، صفحه 300-315 اصل مقاله (168.96 K) | ||
| نوع مقاله: Review Article | ||
| نویسندگان | ||
| Kobra Nikoofar* 1؛ Diba Kadivar2؛ Samaneh Shirzadnia2 | ||
| 1chemistry department, school of sciences, alzahra university, vanak, tehran, i.t.iran | ||
| 2Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran 1993891176, Iran | ||
| چکیده | ||
| Indole is a nitrogen-containing heterocycle. It is a very important motif in agriculture and pharmacy. Many compounds containing indole moiety has been isolated form nature. It is also an important part in natural alkaloids. Tryptophan is an amino acid which posses indole. 3-Sustituted indoles are the main group of its derivatives. Because the wide-spread application of 3-substituted indolic compounds their synthetic procedures are in demand by organic chemists. In this review we have focused on about twenty compound of 3-substituted indole derivatives that showed pharmacological properties. A concise synthetic route for some of them has also been reported. The main pharmaceutical properties of these compounds are antibacterial, anticancer and antimicrobial activities. | ||
| کلیدواژهها | ||
| indole؛ indolyl؛ pharmacy؛ drug؛ Synthesis | ||
| مراجع | ||
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[1] P. Sreejith, R.S. Beyo, L. Divya, A.S. Vijayasree, M. Manju, O.V. Oommen, Indian J. Biochem. Biophys., 2007, 44, 164-168.
[2] Y. Nozaki, C. Tanford, J. Biol. Chem., 1971, 246, 2211-2217.
[3] J. Hajicek, Czech. Chem. Commun., 2007, 72, 821–898.
[4] M.A. Metwally, S. Shaaban, B.F. Abdel-Wahab, G.A. El-Hiti, Curr. Org. Chem., 2009, 13, 1475–1496.
[5] S. Agarwal, S. Cammerer, S. Filali, W. Frohner, J. Knoll, M.P. Krahl, K.R. Reddy, H.J. Knolker, Curr. Org. Chem., 2005, 9, 1601–1614.
[6] M.A.A. Radwan, E.A. Ragab, N.M. Sabry, S.M. El-Shenawy, Bioorg. Med. Chem., 2007, 15, 3832-3841.
[7] J.S. Yadav, B.V.S. Reddy, G. Narasimhulu, N.S. Reddy, P.N. Reddy, K.V. Purnima, P. Naresh, B. Jagadeesh, Tetrahedron Lett., 2010, 51, 244-247.
[8] P. Wu, Y. Wan, J. Cai, Synlett, 2008, 1193-1198.
[9] B.B. Aggarwal, H. Ichikawa, Cell Cycle, 2005, 4, 1201–1215.
[10] J.T. Tsai, H.C. Liu, Y.H. Chen, Mediators Inflamm., 2010, 2936–2942.
[11] G. Hongjing, Ch. Changgui, Z. Lihua, C. Changping, G. Yuanyuan, F. Mingyue, L.Wang, Q. Tang, J. Nut. Biochem., 2013, 24, 62-69.
[12] J.R. Weng, C.H. Tsai, S.K. Kulp, C.S. Chen, Cancer Lett., 2008, 262, 153-163.
[13] J.C. Hsu, A. Dev, A. Wing, C.T. Brew, L.F. Bjeldanes, G.L. Firestone, Biochem. Pharmacol., 2006, 72, 1714-1723.
[14] M. Saegusa, M. Hashimura, T. Kuwata, M. Hamano, I. Okayasu, Int. J. Cancer, 2006, 119, 2294-2303.
[15] H.P. Chang, M.L. Wang, M.H. Chan, Y. Sh. Chiu, Y.H. Chen, Nutrition, 2011, 27, 463-470.
[16] S. Samchai, P. Seephonkai, Ch. Kaewtong, Chinese J. Nat. Medicines, 2011, 9, 173-175.
[17] H.S. Kang, J.H. Choi, W.K. Cho, Arch. Pharm. Res., 2004, 27, 742-750.
[18] S.H. Kim, Y.S. Song, S.K. Kim, J. Ethnopharmacol., 2004, 93, 141-146.
[19] M. Prashad, L.L. Vecchia, K. Prasad, Synth. Commun., 1995, 25, 95-100.
[20] M. Shiri, M.A. Zolfigol, H.G. Kruger, Z. Tanbakouchian, Chem. Rev., 2010,
110, 2250–2293.
[21] K.W. Rahman, Y. Li, Z. Wang, S.H. Sarkar, F.H. Sarkar, Cancer Res., 2006, 66, 4952-4960.
[22] C. Hong, G.L. Firestone, L.F. Bjeldanes, Biochem. Pharmacol., 2002, 63, 1085–1097.
[23] A. Pouilhès, C. Kouklovsky, Y. Langlois, J.-P. Baltaze, S. Vispé, J.-P. Annereau, J.-M. Barret, A. Kruczynskic, C. Bailly, Bioorg. Med. Chem. Lett., 2008, 18, 1212–1216.
[24] E.A. Tsavkelova, T.A. Cherdyntseva, S.G. Botina, A.I. Netrusov, Microbiol. Res., 2007, 162, 69–76.
[25] Md. Mujahid, Ch. Sasikala, Ch.V. Ramana, Appl. Microbiol. Biotechnol., 2011, 89, 1001-1008.
[26] H. Gamal-Eldin, K. Elbanna, Curr. Microbiol., 2011, 62, 391-395.
[27] D. Brewer, W. Jerram, A. Taylor, Can. J. Microbiol., 1968, 14, 861-866.
[28] S. Sekita, Chem. Pharm. Bull., 1983, 31, 2998-3001.
[29] A. Kaji, R. Saito, Y. Hata, N. Kiriyama, Chem. Pharm. Bull., 1999, 47, 77-82.
[30] A. Kaji, T. Iwata, N. Kiriyama, S. Wakusawa, K. Miyamoto, Chem. Pharm. Bull., 1994, 42, 1682-1684.
[31] K.A. Alvi, H. Pu, M. Luche, A. Rice, H. App, G. McMahon, H. Dare B., Margolis, J. Antibiot., 1999, 52, 215-223.
[32] B. Zhang, G. Salituro, D. Szalkowski, Z. Li, Y. Zhang, I. Royo, D. Vilella, M.T. Diez, F. Pelaez, C. Ruby, R. L. Kendall, X. Mao, P. Griffin, J. Calaycay, J.R. Zierath, J.V. Heck, R.G. Smith, D.E. Moller, Science, 1999, 284, 974-977.
[33] P. Singh, P. Verma, B. Yadav, S.S. Komath, Bioorg. Med. Chem. Lett., 2011, 21, 3367-3372.
[34] M. Mazzei, E. Nieddu, M. Miele, A. Balbi, M. Ferrone, M. Fermeglia, M.T. Mazzei, S. Pricl, P. La Colla, F. Marongiu, C. Ibba, R. Loddo, Bioorg. Med. Chem., 2008, 16, 2591-2605.
[35] M.S. Estevão, L.C. Carvalho, D. Ribeiro, D. Couto, M. Freitas, A. Gomes, L.M. Ferreira, E. Fernandes, M. Manuel, B. Marques, Eur. J. Med. Chem., 2010, 45, 4869-4878.
[36] B.V. Subba Reddy, N. Rajeswari, M. Sarangapani, G. Roopa Reddy, Ch. Madan, K. Pranay Kumar, M. Srinivasa Rao, Bioorg. Med. Chem. Lett., 2011, 21, 6510-6514.
[37] M.E. Linday, Practical Introduction to Microbiology, London, E. & F. N. Spon Ltd United Kingdom, 1962.
[38] S.-K. Choi, D. Green, A. Ho, U. Klein, D. Marquess, R. Taylor, S.D. Turner, J.
Med. Chem., 2008, 51, 3609-3616.
[39] J.L. Collins, B.G. Shearer, J.A. Oplinger, S. Lee, E.P. Garvey, M. Salter, C. Duffy, T.C. Burnette, E.S. Furfine, J. Med. Chem., 1998, 41, 2858-2871.
[40] S.C. Annedi, Sh.P. Maddaford, J. Ramnauth, P. Renton, J. Speed, Suman Rakhit ,J.S. Andrews, F. Porreca, Bioorg. Med. Chem. Lett., 2012, 22, 1980–1984.
[41] R.B. Silverman, Acc. Chem. Res., 2009, 42, 439- 451.
[42] R.J. Sundberg, The Chemistry of Indoles,Academic: New York, NY, 1996.
[43] M.M. Ahmed, M.B. El-Saghier, B.K. Naili, N.A. Rammash, M. Saleh Khaled,
Arkivoc, 2007, xvi, 83-91.
[44] R. Tilak, K.B. Richa, K.S. Rakesh, G. Vivek, S. Deepak, P.S.I. Mohan, Eur. J. Med. Chem., 2009, 44, 3209-3216.
[45] C. Cinzia, D. Nicoletta, Bioorg. Med. Chem., 2010, 18, 6480-6488.
[46] R. Hossein nia, M. Mamaghani, Kh. Tabatabaeian, F. Shirini, M. Rassa, Bioorg. Med. Chem. Lett., 2012, 22, 5956–5960.
[47] M. Giampieri, A. Balbi, M. Mazzei, PLa Colla,C. Ibba, R. Loddo, Antiviral Res., 2009, 83, 179-185.
[48] R. Quirion, W.D. Bowen, Y. Itzhak, J.L. Jumien, J.M. Musacchio, R.B. Rothman, T.P. Su, S.W. Tam, D.P. Taylor, Trends Pharmacol. Exp. Ther., 1992, 13, 85-86.
[49] B. Bourrie, E. Bribes, J.M. Derocq, H. Vidal, P. Casellas, Curr. Opin. Invest. Drugs, 2004, 5, 1158-1163.
[50] T. Maurice, T.P. Su, Pharmacol. Ther., 2009, 124, 195-206.
[51] U. Jacquemard, S. Routier, N. Dias, A. Lansiaux, J.F. Goossens, C. Bailly, J.Y. Merour, Eur. J. Med. Chem., 2005, 40, 1087-1095.
[52] M.R. Buemi, L. De Luca, A. Chimirri, S. Ferro, R. Gitto, J. Alvarez-Buill, R. Alajarin, Bioorg. Med. Chem., 2013, 21, 4575-4580.
[53] H. Kumar, H.W. Lim, S.V. More, B.W. Kim, S. Koppula, I.S. Kim, D.K. Choi, Int. J. Mol. Sci., 2012, 13, 10478-10540.
[54] M. Serra, P. Madau, M.F. Chessa, M. Caddeo, E. Sanna, G. Trapani, M. Franco, G. Liso, R.H. Purdy, M.L. Barbaccia, G.B. Bigio, J. Pharmacol., 1999, 127,177- 182.
[55] R.M. Mohareb, H.H. Ahmed, G.A. Elmegeed., M.M. Abd-Elhalim, R.W. Shafic, Bioorg. Med. Chem., 2011, 19, 2966–2974.
[56] N.V. Lakshmi, P. Thirumurugan, K.M. Noorulla, P.T. Perumal, Bioorg. Med. Chem. Lett., 2010, 20, 5054–5061.
[57] Y. Peng, Zh. Zhao, X.Liu, G. Li, Res. Chem. Intermed., 2013, 39, 1897-1905.
[58] J.L. Mi, C.H. Zhou, X. Bai, Chin. J. Antibiot., 2007, 32, 587-593.
[59] J.L. Mi, J. Wu, C.H. Zhou, West Chin. J. Pharm. Sci., 2008, 23, 84-86.
[60] R. Pingaew, S. Prachayasittikul, S. Ruchirawat, V. Prachayasittikul, Mol. Divers., 2013, 17, 595-604.
[61] R. Gupta, A. Jain, R. Joshi, M. Jain, Bull. Korean Chem. Soc., 2011, 32, 899-904.
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